It doesn't include all specifics of the probable uses, Instructions, warnings, safety measures, interactions, adverse results, or hazards that may use to modafinil. This information and facts will not be precise health care suggestions and won't exchange data you get within the Health care provider. You will need to talk to the healthcare service provider for finish details about the threats and benefits of working with this medicine.
In case you overlook a dose, get it the moment you may. If it is nearly time in your future dose, choose only that dose. Tend not to acquire double or excess doses.
istradefylline will boost the amount or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Much more than 50% of amphetamine group described signs or symptoms of excitation, pleasure, and dry mouth. Modafinil group wasn't noticeably distinctive from placebo group in adverse outcomes.
Contraindicated (2)modafinil will enhance the degree or influence of mavacamten by impacting hepatic enzyme CYP2C19 metabolism. Contraindicated. Solid or average CYP2C19 inhibitors might enhance mavacamten systemic get more info publicity, causing heart failure as a consequence of systolic dysfunction.
efavirenz will minimize the level or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
When you've got been using this medicine for years or in significant doses and you think that maybe you have become mentally or physically depending on it, Test with your health practitioner. Some signs of dependence on modafinil are:
Reassess diploma of sleepiness commonly; if utilized adjunctively with continual optimistic airway tension (CPAP): Periodic evaluation of CPAP compliance is essential
Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig revurdere langtidsbruk for den enkelte pasient ettersom effekten av modafinil ved langtidsbruk ikke har blitt studert (>9 uker). Spesielle pasientgrupper Nedsatt leverfunksjon: Ved alvorlig nedsatt leverfunksjon bør dosen halveres.
cenobamate will improve the level or influence of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Carefully. Consider a dose reduction of CYP2C19 substrates, as clinically ideal, when employed concomitantly with cenobamate.
modafinil will decrease the level or impact of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
In South Africa, modafinil is Plan V material, which suggests that it's authorized to employ modafinil in South Africa, but only with a legitimate prescription from the licensed healthcare practitioner.[211]
Although modafinil is generally observed to become Risk-free and important adverse consequences are uncommon, together with in pediatric narcolepsy cases (rest Conditions in small children), There's evidence that lengthy-term usage can result in tolerance in some people.
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